ESPEN Chronic Intestinal Failure Research Study

The 2025 data collection of The ESPEN Chronic Intestinal Failure Research Study is going to start.

Those CIF/HPN centres that are not yet contributing and are willing to join the database community, can easily do it by sending the request to espencifday@gmail.com, with the following information:

• First name
• Middle initial(s)
• Surname
• Affiliation:
• Hospital name
• City
• Country
• Address
• Phone
• Fax
• email
• CIF age category in your center (adult, pediatric or both)
• Year of starting HPN activity

The requesting centres will receive the study protocol and the database for data collection. Participation is subject to the regulation and approval of the local Ethics Committee. 

The ESPEN CIF database was developed in 2015. To carry out the study protocol “A prospective multicenter study to know the outcome of patient with CIF”,

Up today, 159 Centres from 40 Countries included 18180 patients (adults and children)

The following papers from the CIF database have been published:

1. Clinical classification of adult patients with chronic intestinal failure due to benign disease: an international multicenter cross-sectional survey. Clin Nutr. 2018 Apr;37(2):728-738.
2. Revised ESPEN Clinical Classification of Chronic Intestinal Failure: From 16 to 8 Categories. JPEN J Parenter Enteral Nutr. 2017 Aug;41(6):911
3. Home parenteral nutrition provision modalities for chronic intestinal failure in adult patients: An international survey. Clin Nutr. 2020 Feb;39(2):585-591.
4. Intravenous supplementation type and volume are associated with 1-year outcome and major complications in patients with chronic intestinal failure. Gut. 2020 Oct;69(10):1787-1795
5. Characteristics of adult patients with chronic intestinal failure due to short bowel syndrome: An international multicenter survey. Clin Nutr ESPEN. 2021 Oct;45:433-441.
6. Chronic Intestinal Failure in Children: An International Multicenter Cross-Sectional Survey. Nutrients. 2022 Apr 30;14(9):1889.
7. Characteristics of adult patients with chronic intestinal failure due to short bowel syndrome: An international multicenter survey. Clin Nutr ESPEN. 2021
8. COVID-19 infection in patients on long-term home parenteral nutrition for chronic intestinal failure. Clin Nutr ESPEN. 2023 Jun;55:212-220
9. Real-world experience of Teduglutide use in adults with short bowel syndrome: a seven-year international multicenter survey. Clin Nutr, accepted 2025

All the contributing centres shared the co-authorship.